منابع مشابه
The blood platelet in transfusion therapy.
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متن کاملRefractory response to platelet transfusion therapy.
Platelet transfusions are commonly used for prophylaxis and treatment of bleeding. After a transfusion, an increment or "boost" is expected to occur. While a number of factors can contribute to a poor posttransfusion increment, refractoriness is typically defined as failure to achieve an appropriate increment after receiving 2 consecutive transfusions with fresh ABO-compatible platelets. The mo...
متن کاملPlatelet Transfusion – The New Immunology of an Old Therapy
Platelet transfusion has been a vital therapeutic approach in patients with hematologic malignancies for close to half a century. Randomized trials show that prophylactic platelet transfusions mitigate bleeding in patients with acute myeloid leukemia. However, even with prophylactic transfusions, as many as 75% of patients, experience hemorrhage. While platelet transfusion efficacy is modest, q...
متن کاملHLA-matched platelet transfusion therapy of severe aplastic anemia.
In order to define more clearly the importance of the degree of HLA compatibility in the hematologic support of patients refractory to random-donor platelets, we retrospectively analyzed over 1 000 platelet transfusions given during stable periods of their disease to 1 1 thrombocytopenic, severely alloimmunized patients with aplastic anemia: 28% of the donors fully matched with the recipient fo...
متن کاملThrombocytopenia and platelet transfusion
Thrombocytopenia is caused by disorders impairing platelet production, causing platelet destruction or leading to platelet sequestration. In addition, there are both congenital and acquired disorders of platelet function. These latter conditions may lead to the functional equivalent of thrombocytopenia, often despite the presence of a normal platelet count. Platelet transfusion represents an im...
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ژورنال
عنوان ژورنال: Journal of the Japan Society of Blood Transfusion
سال: 1994
ISSN: 1883-8383,0546-1448
DOI: 10.3925/jjtc1958.40.821